Integrating genomics, big data, and computing to drive biological discoveries and medical innovations

Highlighted Publications

Xin R*, Gao Y*, Gao Y, Wang R, Kadash-Edmondson KE, Liu B, Wang Y, Lin L, Xing Y. (2021) isoCirc catalogs full-length circular RNA isoforms in human transcriptomes. Nature Communications, 12:266. (*joint first authors)

Phillips JW*, Pan Y*, Tsai BL, Xie Z, Demirdjian L, Xiao W, Yang HT, Zhang Y, Lin CH, Cheng D, Hu Q, Liu S, Black DL, Witte ON+, Xing Y+. (2020) Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers. PNAS, 117(10):5269-79. (+joint corresponding authors; *joint first authors)

Zhang Z*, Pan Z*, Ying Y, Xie Z, Adhikari S, Phillips J, Carstens RP, Black DL, Wu Y, Xing Y. (2019) Deep learning-augmented RNA-seq analysis of transcript splicing. Nature Methods, 16:307-10. (*joint first authors)

Molinie B*, Wang J*, Lim KS, Hillebrand R, Lu ZX, Van Wittenberghe N, Howard BD, Daneshvar K, Mullen A, Dedon P, Xing Y+, Giallourakis CC.+ (2016) m6A level and isoform characterization sequencing (m6A-LAIC-seq) reveals the census and complexity of the m6A epitranscriptomeNature Methods, 13(8):692-8. (+joint corresponding authors; *joint first authors).

Shen S*Park JW*Lu ZXLin L, Henry MD, Wu YN, Zhou Q, Xing Y. (2014) rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data. PNAS, 111(51):E5593-601. (*joint first authors).

Find Us

The Xing Lab is located on the 9th floor of the Colket Translational Research Building.

The Children’s Hospital of Philadelphia
9054 Colket Translational Research Bldg.
3501 Civic Center Blvd.
Philadelphia, PA 19104
(215) 590-0280